Scan time minimization in hepatic diffusion-weighted imaging: evaluation of the simultaneous multislice acceleration technique with different acceleration factors and gradient preparation schemes

Abstract

To evaluate simultaneous multislice (sms) accelerated diffusion-weighted imaging (DWI) of the liver in comparison to conventional sequences. Ten volunteers underwent DWI of the liver at 1.5 T. Four different sms-accelerated sequences with monopolar and bipolar gradient preparation (MP, BP) and acceleration factors 2 and 3 (sms2-DWI, sms3-DWI) were compared to conventional DWI (c-DWI). Image quality criteria rated on a 5-point Likert scale (5 = excellent), image quality sum scores (maximum 120), and ADC were compared using Friedman test and Dunn-Bonferroni post hoc test. Bland–Altman plots were calculated for ADC comparison. p values <0.05 were considered significant. Sms2-DWI offered scan time minimization of 67 % without significant difference in image quality (sum score: sms2-DWI MP/BP: 97 ± 8/92 ± 9; c-DWI MP/BP: 99 ± 8/97 ± 8). Sms3-DWI offered slight additional scan time minimization with significantly inferior image quality (sum score: sms3-DWI MP/BP: 75 ± 14/69 ± 14; p < 0.001). MP preparation provided slightly higher image quality in sms-DWI without statistical significance. ADC in sms-DWI were significantly lower (sms2-DWI MP 1.01 × 10−3 mm2/s; c-DWI MP 1.20 × 10−3 mm2/s; p < 0.001). Sms2-DWI provides considerable scan time minimization without significant shortcomings in image quality. Sms3-DWI provides significantly inferior image quality without further scan time minimization. Potentially lower ADC in sms-DWI should be considered in clinical routine.

DOI: 10.1007/s10334-016-0553-4

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Cite this paper

@article{Taron2016ScanTM, title={Scan time minimization in hepatic diffusion-weighted imaging: evaluation of the simultaneous multislice acceleration technique with different acceleration factors and gradient preparation schemes}, author={Jana Taron and Petros Martirosian and N. Schwenzer and Michael Erb and Thomas K{\"{u}stner and Jakob Weiss and A E Othman and Mike Notohamiprodjo and Konstantin Nikolaou and Christina Schraml}, journal={Magnetic Resonance Materials in Physics, Biology and Medicine}, year={2016}, volume={29}, pages={739-749} }