Scalusamides A-C, new pyrrolidine alkaloids from the marine-derived fungus Penicillium citrinum.

@article{Tsuda2005ScalusamidesAN,
  title={Scalusamides A-C, new pyrrolidine alkaloids from the marine-derived fungus Penicillium citrinum.},
  author={Masashi Tsuda and Mai Sasaki and Takao Mugishima and Kazusei Komatsu and Teruo Sone and Michiko Tanaka and Yuzuru Mikami and Jun'ichi Kobayashi},
  journal={Journal of natural products},
  year={2005},
  volume={68 2},
  pages={273-6}
}
Three new pyrrolidine alkaloids, scalusamides A-C (1-3), were isolated from the cultured broth of the fungus Penicillium citrinum, which was separated from the gastrointestine of a marine fish, and the structures were elucidated by spectroscopic data. The absolute stereochemistry of C-2 in the pyrrolidine unit was determined by HPLC analysis of a Marfey's derivative of the hydrolysate of 1, while that of 2 and 3 was assigned by comparison of spectroscopic data of 3 and reductive products of 1… CONTINUE READING