Scaling of diastolic intraventricular pressure gradients is related to filling time duration.

@article{Popovi2006ScalingOD,
  title={Scaling of diastolic intraventricular pressure gradients is related to filling time duration.},
  author={Zoran B Popovi{\'c} and Kathryn E Richards and Neil L. Greenberg and Aleksandr L. Rovner and Jeannie K Drinko and Yuanna Cheng and Marc S. Penn and Kiyotaka Fukamachi and Niladri Mal and Benjamin D Levine and Mario J. Garcia and James D. Thomas},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2006},
  volume={291 2},
  pages={H762-9}
}
In early diastole, pressure is lower in the apex than in the base of the left ventricle (LV). This early intraventricular pressure difference (IVPD) facilitates LV filling. We assessed how LV diastolic IVPD and intraventricular pressure gradient (IVPG), defined as IVPD divided by length, scale to the heart size and other physiological variables. We studied 10 mice, 10 rats, 5 rabbits, 12 dogs, and 21 humans by echocardiography. Color Doppler M-mode data were postprocessed to reconstruct IVPD… CONTINUE READING

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References

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Scaling of diastolic intraventricular pressure gradients is related to filling time duration

Kathryn E. Richards, Neil L. Greenberg, +6 authors James D. Thomas
Am J Physiol Heart Circ Physiol • 2006

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