Scale-down of the inactivated polio vaccine production process.

@article{Thomassen2013ScaledownOT,
  title={Scale-down of the inactivated polio vaccine production process.},
  author={Yvonne Elisabeth Thomassen and Aart G van 't Oever and Marian Vinke and Arjen Spiekstra and Ren{\'e} H. Wijffels and Leo A. van der Pol and Wilfried A. M. Bakker},
  journal={Biotechnology and bioengineering},
  year={2013},
  volume={110 5},
  pages={
          1354-65
        }
}
The anticipated increase in the demand for inactivated polio vaccines resulting from the success in the polio eradication program requires an increase in production capacity and cost price reduction of the current inactivated polio vaccine production processes. Improvement of existing production processes is necessary as the initial process development has been done decades ago. An up-to-date lab-scale version encompassing the legacy inactivated polio vaccine production process was set-up. This… CONTINUE READING
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