Scalable production of transplantable dopaminergic neurons from hESCs and iPSCs in xeno-free defined conditions.

Abstract

Human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are potentially an unlimited cell source for cell replacement therapy and personalized medicine. Before hESC- and iPSC-based therapy can be moved from bench to bedside, however, it is essential to establish protocols for generating therapeutically relevant cells, like dopaminergic… (More)
DOI: 10.1002/9780470151808.sc02d12s22

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