Scalable preparation of both enantiomers of 2-(1-hydroxy-2-oxocyclohexyl)acetic acid.

@article{Vamos2008ScalablePO,
  title={Scalable preparation of both enantiomers of 2-(1-hydroxy-2-oxocyclohexyl)acetic acid.},
  author={Mitchell Dennis Vamos and Yoshihisa Kobayashi},
  journal={The Journal of organic chemistry},
  year={2008},
  volume={73 10},
  pages={
          3938-41
        }
}
The efficient, scalable preparation of both enantiomers of 2-(1-hydroxy-2-oxocyclohexyl)acetic acid in enantiomerically pure form is reported using environmentally benign conditions in 30% overall yield (6 steps) for the (S)-isomer, in 27% (7 steps) for the (R)-isomer, from cyclohexanone. 
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