Scaffolding proteins and non-proliferative functions of ERK1/2.

Abstract

Studies of ERK1/2 generally focus on the regulation of nuclear ERK1/2 function mainly related to proliferation, whereas less attention has been drawn to the role ERK1/2 plays in the cytosol. Scaffolding proteins for ERK1/2 have been shown to control the time point and also the intracellular location of ERK1/2 activation. Hence, by concentrating ERK1/2… (More)

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