Scaffolding protein GOPC regulates tight junction structure

@article{Lu2014ScaffoldingPG,
  title={Scaffolding protein GOPC regulates tight junction structure},
  author={Ruifeng Lu and Lorraine Stewart and Jean M Wilson},
  journal={Cell and Tissue Research},
  year={2014},
  volume={360},
  pages={321-332}
}
GOPC (FIG/PIST/CAL) is a PDZ-domain scaffolding protein that regulates the trafficking of a wide array of proteins, including small GTPases, receptors and cell surface molecules such as cadherin 23 and cystic fibrosis transmembrane regulator. In Madin-Darby canine kidney (MDCK) cells, we find that GOPC localizes to the trans-Golgi network (TGN) but not to the cis- or trans-Golgi cisternae. Colocalization occurs with the early endosome Rab GTPase Rab5 and a TGN/endosome marker Rab14 but not with… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

AMPA receptor synaptic targeting regulated by stargazin interactions with the Golgi-resident PDZ protein nPIST.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2004
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…