Scaffold-free vascular tissue engineering using bioprinting.

  title={Scaffold-free vascular tissue engineering using bioprinting.},
  author={Cyrille Norotte and Francois S Marga and Laura E. Niklason and Gabor Forgacs},
  volume={30 30},
Current limitations of exogenous scaffolds or extracellular matrix based materials have underlined the need for alternative tissue-engineering solutions. Scaffolds may elicit adverse host responses and interfere with direct cell-cell interaction, as well as assembly and alignment of cell-produced ECM. Thus, fabrication techniques for production of scaffold-free engineered tissue constructs have recently emerged. Here we report on a fully biological self-assembly approach, which we implement… CONTINUE READING
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