Scaffold assembly based on genome rearrangement analysis

  title={Scaffold assembly based on genome rearrangement analysis},
  author={Sergey Aganezov and Nadia Sitdykova and Max A. Alekseyev},
  journal={Computational biology and chemistry},
Advances in DNA sequencing technology over the past decade have increased the volume of raw sequenced genomic data available for further assembly and analysis. While there exist many algorithms for assembly of sequenced genomic material, they often experience difficulties in constructing complete genomic sequences. Instead, they produce long genomic subsequences (scaffolds), which then become a subject to scaffold assembly aimed at reconstruction of their order along genome chromosomes. The… CONTINUE READING
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Scaffold assembly based on genome rearrangement analysis

  • S. Aganezov, N. Sydtnikova, AGC Consortium, M. A. Alekseyev
  • Computational Biology and Chemistry
  • 2015
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