Say NO to neurodegeneration: role of S-nitrosylation in neurodegenerative disorders.

@article{Chung2006SayNT,
  title={Say NO to neurodegeneration: role of S-nitrosylation in neurodegenerative disorders.},
  author={Kenny K. K. Chung},
  journal={Neuro-Signals},
  year={2006},
  volume={15 6},
  pages={307-13}
}
Nitric oxide (NO) is an important signaling molecule that controls a wide range of biological processes. One of the signaling mechanisms of NO is through the S-nitrosylation of cysteine residues on proteins. S-nitrosylation is now regarded as an important redox signaling mechanism in the regulation of different cellular and physiological functions. However, deregulation of S-nitrosylation has also been linked to various human diseases such as neurodegenerative disorders. Nitrosative stress has… CONTINUE READING

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Emerging roles of nitric oxide in neurodegeneration.

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S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2010
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