Saturation of conductance in single ion channels: the blocking effect of the near reaction field.

@article{Nadler2004SaturationOC,
  title={Saturation of conductance in single ion channels: the blocking effect of the near reaction field.},
  author={Boaz Nadler and Zeev Schuss and Uwe Hollerbach and Robert S. Eisenberg},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2004},
  volume={70 5 Pt 1},
  pages={051912}
}
The ionic current flowing through a protein channel in the membrane of a biological cell depends on the concentration of the permeant ion, as well as on many other variables. As the concentration increases, the rate of arrival of bath ions to the channel's entrance increases, and typically so does the net current. This concentration dependence is part of… CONTINUE READING