Saturation and base composition bias explain phylogenomic conflict in Plasmodium.

@article{Dvalos2008SaturationAB,
  title={Saturation and base composition bias explain phylogenomic conflict in Plasmodium.},
  author={Liliana M D{\'a}valos and Susan L. Perkins},
  journal={Genomics},
  year={2008},
  volume={91 5},
  pages={433-42}
}
Despite recent genome-based advances in understanding Plasmodium molecular evolution and its relationship to disease mechanisms and potential drug development, the phylogenetics of the group is currently limited to single-gene analyses. Here we develop and analyze a set of N100 putative orthologous genes derived from genome comparisons. We aimed to minimize systematic errors that arise when reconstructing the Plasmodium phylogeny with a genome-scale data set by evaluating the congruence of… CONTINUE READING

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