Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial

@article{Nurmikko2007SativexST,
  title={Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial},
  author={Turo J. Nurmikko and Michael G. Serpell and Barbara Hoggart and P. J. Toomey and Derek R Haines},
  journal={PAIN®},
  year={2007},
  volume={133},
  pages={210-220}
}
Cannabinoids are known to have analgesic properties. We evaluated the effect of oro-mucosal sativex, (THC: CBD), an endocannabinoid system modulator, on pain and allodynia, in 125 patients with neuropathic pain of peripheral origin in a five-week, randomised, double-blind, placebo-controlled, parallel design trial. Patients remained on their existing stable analgesia. A self-titrating regimen was used to optimise drug administration. Sixty-three patients were randomised to receive sativex and… CONTINUE READING

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