Satellite glial cells in sympathetic and parasympathetic ganglia: In search of function

  title={Satellite glial cells in sympathetic and parasympathetic ganglia: In search of function},
  author={Menachem Hanani},
  journal={Brain Research Reviews},
  • M. Hanani
  • Published 24 September 2010
  • Biology
  • Brain Research Reviews
Satellite glial cells in the nodose ganglion of the rat vagus nerve: Morphologicalalterations of microglial cells.
Findings would indicate that the SGCs respond to environmental changes of neuronal cell bodies are reactive microglial cells in the NG, and Iba-1- immunoreactive cells seem to be extending a part of the glial cell bodies into neurons in theNG.
Satellite glial cells modulate cholinergic transmission between sympathetic neurons
It is shown that satellite glia regulate postnatal development and activity of sympathetic neurons, providing evidence for local ganglionic control of sympathetic drive and expanding the understanding of the contributions of local and target-derived factors in the regulation of sympathetic neuron function.
Emerging importance of satellite glia in nervous system function and dysfunction
How SGCs are altered in rodent models of four common types of pain: systemic inflammation (sickness behaviour), post-surgical pain, diabetic neuropathic pain and post-herpetic pain is described.
General Pathophysiology of Neuroglia: Neurological and Psychiatric Disorders as Gliopathies
Homeostatic functions of neu- roglia also extend to forming the defense of the nervous system and are ultimately involved in pathogenesis of many (if not all) brain disorders.
The Purinergic System and Glial Cells: Emerging Costars in Nociception
Existing evidence of novel “druggable” glial purinergic targets, which could help in the development of innovative analgesic approaches to chronic pain states are summarized.
P2X Receptors and Their Roles in Astroglia in the Central and Peripheral Nervous System
Astroglia detect by P2X1/5 and P2 X7 receptors both physiological concentrations of ATP secreted from presynaptic nerve terminals and also much higher concentrations ofATP attained under pathological conditions.
The Concept of Neuroglia.
This concept presented in this chapter serves as a general introduction into the world of neuroglia and subsequent topics covered by this book.


Ultrastructure of Ganglionic Junctions
There are striking differences among various vertebrate groups and among various ganglia in the arrangement of these synapses in relation to the postganglionic neurons, which are reflected in the function of the ganglia, influencing, for example, such questions as the security of transmission and the occurrence of convergence or divergence of pre ganglionic input.
Glia: the fulcrum of brain diseases
The brain pathology, is, to a very great extent, a pathology of glia, which, when falling to function properly, determines the degree of neuronal death, the outcome and the scale of neurological deficit.
An ultrastructural study of mammalian cardiac ganglia.
Neuronal somatic ATP release triggers neuron–satellite glial cell communication in dorsal root ganglia
Strong evidence is provided that somata of DRG neurons actively release transmitters and play a crucial role in bidirectional communication between neurons and surrounding satellite glial cells, and this results suggest that, contrary to the conventional view, neuronal somata have a significant role in cell–cell signaling.
Glial cells promote dendritic development in rat sympathetic neurons in vitro
The morphology of embryonic rat sympathetic neurons grown in the absence and in the presence of ganglionic nonneuronal cells in serum‐free medium is compared to indicate that glia selectively promote dendritic development in sympathetic neurons maintained in serum-free medium.
The fine structure of the ganglia of the guinea-pig trachea
The parasympathetic ganglia of the guinea-pig trachea have been investigated by scanning and transmission electron microscopy and an unusual feature of the cytoplasm of the satellite and Schwann cells is the abundance of 10 nm intermediate filaments.
Purinergic neuron-to-glia signaling in the enteric nervous system.
Data from pharmacologic profiling and immunohistochemical analyses support the hypothesis that P2Y4 is the major functional receptor underlying the ATP response in enteric glia, and provide direct evidence for functional purinergic neuron-glia communication in the enteric nervous system.