Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage.

@article{Relaix2012SatelliteCA,
  title={Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage.},
  author={Fr{\'e}d{\'e}ric Relaix and Peter S Zammit},
  journal={Development},
  year={2012},
  volume={139 16},
  pages={2845-56}
}
Following their discovery in 1961, it was speculated that satellite cells were dormant myoblasts, held in reserve until required for skeletal muscle repair. Evidence for this accumulated over the years, until the link between satellite cells and the myoblasts that appear during muscle regeneration was finally established. Subsequently, it was demonstrated that, when grafted, satellite cells could also self-renew, conferring on them the coveted status of 'stem cell'. The emergence of other cell… CONTINUE READING
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