Satellite cell activation in human skeletal muscle after training: evidence for muscle fiber neoformation.

@article{Appell1988SatelliteCA,
  title={Satellite cell activation in human skeletal muscle after training: evidence for muscle fiber neoformation.},
  author={H. J. Appell and Sinikka Forsberg and Wildor Hollmann},
  journal={International journal of sports medicine},
  year={1988},
  volume={9 4},
  pages={297-9}
}
In subjects who had undergone monopedal bicycle ergometer work for 30 min 4 days a week for 6 weeks under aerobic conditions, biopsies from the M. vastus lateralis were studied in the light and electron microscope. In some cases very small myofibers with central nuclei were found. At the ultrastructural level, these fibers turned out to be myotubes. The satellite cells occasionally appeared to be activated and to fuse with muscle fibers. It was concluded that these observations represented… CONTINUE READING

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