Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation

@article{Yasuda2019Satb1RT,
  title={Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation},
  author={K. Yasuda and Y. Kitagawa and Ryoji Kawakami and Y. Isaka and H. Watanabe and G. Kondoh and T. Kohwi-Shigematsu and S. Sakaguchi and K. Hirota},
  journal={Nature Communications},
  year={2019},
  volume={10}
}
The genome organizer, special AT-rich sequence-binding protein-1 (Satb1), plays a pivotal role in the regulation of global gene networks in a cell type-dependent manner and is indispensable for the development of multiple cell types, including mature CD4+ T, CD8+ T, and Foxp3+ regulatory T cells in the thymus. However, it remains unknown how the differentiation and effector program of the Th subsets in the periphery are regulated by Satb1. Here, we demonstrate that Satb1 differentially… Expand
9 Citations
SATB1-mediated chromatin landscape in T cells
  • 1
Differential SATB1 expression reveals heterogeneity of cutaneous T cell lymphoma.
  • Y. Gao, F. Liu, +4 authors Yang Wang
  • Biology, Medicine
  • The Journal of investigative dermatology
  • 2020
The pathogenicity of Th17 cells in autoimmune diseases
  • 50
Gut dysbiosis contributes to the imbalance of Treg and Th17 cells in Graves' disease patients by propionic acid.
  • 3
Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities
  • 4
  • Highly Influenced
  • PDF

References

SHOWING 1-10 OF 77 REFERENCES
CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity
  • 184
  • PDF
JunB is essential for IL-23-dependent pathogenicity of Th17 cells
  • 30
  • PDF
Essential Roles of SATB1 in Specifying T Lymphocyte Subsets.
  • 35
Induction of pathogenic Th17 cells by inducible salt sensing kinase SGK1
  • 665
  • PDF
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
  • 164
  • PDF
...
1
2
3
4
5
...