Sas10 controls ribosome biogenesis by stabilizing Mpp10 and delivering the Mpp10–Imp3–Imp4 complex to nucleolus

@article{Zhao2019Sas10CR,
  title={Sas10 controls ribosome biogenesis by stabilizing Mpp10 and delivering the Mpp10–Imp3–Imp4 complex to nucleolus},
  author={Shuyi Zhao and Yayue Chen and F. Chen and Delai Huang and Hui Shi and L. Lo and J. Chen and J. Peng},
  journal={Nucleic Acids Research},
  year={2019},
  volume={47},
  pages={2996 - 3012}
}
Abstract Mpp10 forms a complex with Imp3 and Imp4 that serves as a core component of the ribosomal small subunit (SSU) processome. Mpp10 also interacts with the nucleolar protein Sas10/Utp3. However, it remains unknown how the Mpp10–Imp3–Imp4 complex is delivered to the nucleolus and what biological function the Mpp10–Sas10 complex plays. Here, we report that the zebrafish Mpp10 and Sas10 are conserved nucleolar proteins essential for the development of the digestive organs. Mpp10, but not… Expand
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References

SHOWING 1-10 OF 44 REFERENCES
...
1
2
3
4
5
...