Sarcoplasmic reticulum proteins in heart failure.


Altered calcium homeostasis may play a key role in the pathophysiology of human heart failure. Levels of sarcoplasmic reticulum (SR) proteins and sarcolemmal Na(+)-Ca2+ exchanger were analyzed by Western blot in failing and nonfailing human myocardium and related to myocardial function. Levels of the SR calcium release channel and of calcium storage… (More)


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@article{Lehnart1998SarcoplasmicRP, title={Sarcoplasmic reticulum proteins in heart failure.}, author={Stephan E. Lehnart and Wolfgang Schillinger and Burkert Pieske and Juergen Prestle and Hanjoerg Just and Gerd Hasenfuss}, journal={Annals of the New York Academy of Sciences}, year={1998}, volume={853}, pages={220-30} }