Sarcoplasmic reticulum Ca2+ release flux underlying Ca2+ sparks in cardiac muscle.

@article{Blatter1997SarcoplasmicRC,
  title={Sarcoplasmic reticulum Ca2+ release flux underlying Ca2+ sparks in cardiac muscle.},
  author={Lothar A Blatter and J{\"o}rg H{\"u}ser and Eduardo R{\'i}os},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 8},
  pages={
          4176-81
        }
}
Discrete events of Ca2+ release from the sarcoplasmic reticulum (SR) have been described in cardiac, skeletal, and smooth muscle. In skeletal muscle these release events originate at individual channels. In cardiac muscle, however, it remains a question of debate whether localized Ca2+ release transients, termed Ca2+ sparks, originate from single release channels or multiple channels clustered in close vicinity. Generalizing methods used earlier to describe cell-averaged Ca2+ release, we… CONTINUE READING

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