Sarcopenia and change in body composition following maximal androgen suppression with abiraterone in men with castration-resistant prostate cancer

  • Carmel Jo Pezaro, D Mukherji, +8 authors G Attard
  • Published 2013 in British Journal of Cancer

Abstract

Background:Standard medical castration reduces muscle mass. We sought to characterize body composition changes in men undergoing maximal androgen suppression with and without exogenous gluocorticoids.Methods:Cross-sectional areas of total fat, visceral fat and muscle were measured on serial CT scans in a post-hoc analysis of patients treated in Phase I/II… (More)
DOI: 10.1038/bjc.2013.340