Sarcopenia: a histological and immunohistochemical study on age-related muscle impairment

@article{Tarantino2015SarcopeniaAH,
  title={Sarcopenia: a histological and immunohistochemical study on age-related muscle impairment},
  author={U. Tarantino and M. Scimeca and Eleonora Piccirilli and V. Tancredi and J. Baldi and E. Gasbarra and E. Bonanno},
  journal={Aging Clinical and Experimental Research},
  year={2015},
  volume={27},
  pages={51-60}
}
BackgroundSarcopenia and osteoporosis increase the risk of bone fracture in the elderly due to the loss of muscle mass and the decrease in bone mineral density. Myostatin and Bone Morphogenetic Proteins (BMPs) are important molecules involved in muscle mass homeostasis.AimIn this study, we investigated the role of BMP4 and myostatin in the pathophysiogenesis of sarcopenia related to osteoporosis and osteoarthritis.MethodsMuscle atrophy, BMP4 and myostatin expression were evaluated in 27… Expand
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