Sarcopenia: Alternative Definitions and Associations with Lower Extremity Function

  title={Sarcopenia: Alternative Definitions and Associations with Lower Extremity Function},
  author={Anne B. Newman and Varant Kupelian and Marjolein Visser and Eleanor M. Simonsick and Bret H. Goodpaster and Michael A Nevitt and Stephen B. Kritchevsky and Frances A Tylavsky and Susan M. Rubin and Tamara B. Harris},
  journal={Journal of the American Geriatrics Society},
Objectives: To compare two sarcopenia definitions and examine the relationship between them and lower extrem‐ity function and other health related factors using data from the baseline examination of the Health Aging and Body Composition (Health ABC) Study. 

Sarcopenia, and its association with cardiometabolic and functional characteristics in Taiwan: Results from I‐Lan Longitudinal Aging Study

Evaluated the prevalence of sarcopenia and its associative clinical characteristics in Taiwan and found that it is a well‐recognized geriatric syndrome which is associated with a variety of adverse outcomes.

Loss of Muscle Strength, Mass (Sarcopenia), and Quality (Specific Force) and Its Relationship with Functional Limitation and Physical Disability: The Concord Health and Ageing in Men Project

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Variation in the Prevalence of Sarcopenia and Sarcopenic Obesity in Older Adults Associated with Different Research Definitions: Dual‐Energy X‐Ray Absorptiometry Data from the National Health and Nutrition Examination Survey 1999–2004

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Qualitative muscle mass index as a predictor of skeletal muscle function deficit in Asian older adults

The present cross‐sectional study was carried out among community‐dwelling Koreans to determine the validity of various muscle mass indices and to propose more clinically relevant diagnostic criteria.

Relative Contributions of Adiposity and Muscularity to Physical Function in Community‐dwelling Older Adults

To determine the relative contributions of adiposity and muscularity to multi‐dimensional performance‐based and perceived physical function in older adults living independently, a large number of them are female.

Physical Activity Decreases the Risk of Sarcopenia and Sarcopenic Obesity in Older Adults with the Incidence of Clinical Factors: 24-Month Prospective Study.

The occurrence of sarcopenia and sarcopenic obesity may be associated with modifiable behavioral factors such as insufficient physical activity and sedentary behaviour, which may have an impact on obesity and mortality.

Effects of different definitions of low muscle mass on its association with metabolic syndrome in older adults: A Korean nationwide study

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Importance of physical evaluation using skeletal muscle mass index and body fat percentage to prevent sarcopenia in elderly Japanese diabetes patients

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Sarcopenia among patients receiving hemodialysis: weighing the evidence

Four definitions of low muscle mass in a prevalent hemodialysis cohort are compared and it is found that use of muscle mass normalized to height‐squared may underestimate sarcopenia, particularly in the setting of excess adiposity.



Low Relative Skeletal Muscle Mass (Sarcopenia) in Older Persons Is Associated with Functional Impairment and Physical Disability

OBJECTIVES: To establish the prevalence of sarcopenia in older Americans and to test the hypothesis that sarcopenia is related to functional impairment and physical disability in older persons.

Leg Muscle Mass and Composition in Relation to Lower Extremity Performance in Men and Women Aged 70 to 79: The Health, Aging and Body Composition Study

The aim was to determine whether low leg muscle mass and greater fat infiltration in the muscle were associated with poor lower extremity performance (LEP).

Epidemiology of Sarcopenia

To examine patterns of muscle mass change with aging and to estimate the prevalence of sarcopenia, a large number of patients with confirmed or suspected cases of sarc Openia undergoes programmed cell death.

Departures from linearity in the relationship between measures of muscular strength and physical performance of the lower extremities: the Women's Health and Aging Study.

There is a departure from linearity in the relationship between muscular strength and some measures of lower extremity performance in this population of women, which does not include the strongest older women.

Appendicular lean tissue mass and the prevalence of sarcopenia among healthy women.

Results of the present study provide further evidence that sarcopenia exists even among otherwise healthy women with increasing age-specific prevalence and to find therapeutic strategies with beneficial effects in conserving skeletal muscle mass.

Functional and metabolic consequences of sarcopenia.

  • W. Evans
  • Medicine, Education
    The Journal of nutrition
  • 1997
Exercise may minimize or reverse the syndrome of physical frailty prevalent among very old individuals, and there is no segment of the population that can benefit more from exercise training than the elderly.

Associations of body composition with physical performance and self-reported functional limitation in elderly men and women.

It is suggested that fat mass negatively impacts some domains of physical performance and overall functioning, while lean mass is less significant in absolute terms but is important relative to amount of body fat.

Sarcopenic Obesity: Does Muscle Loss Cause Fat Gain?: Lessons from Rheumatoid Arthritis and Osteoarthritis a

  • R. Roubenoff
  • Medicine
    Annals of the New York Academy of Sciences
  • 2000
RA is a useful model of cachexia uncomplicated by wasting because malabsorption, liver dysfunction, and renal dysfunction are not normally part of RA, and uniform diagnostic criteria are available, this disease offers an excellent model to study chronic hypercytokinemic cachexia.

Epidemiology of sarcopenia among the elderly in New Mexico.

Some of the first estimates of the extent of the public health problem posed by sarcopenia are provided, independent of ethnicity, age, morbidity, obesity, income, and health behaviors.

From the Chicago MeetingsSarcopenia

Sarcopenia is a term utilized to define the loss of muscle mass and strength that occurs with aging. Sarcopenia is believed to play a major role in the pathogenesis of frailty and functional