Sarcomere mutations in cardiomyopathy with left ventricular hypertrabeculation.

  title={Sarcomere mutations in cardiomyopathy with left ventricular hypertrabeculation.},
  author={Lisa M. Dellefave and Peter Pytel and Stephanie K. Mewborn and Bassem N Mora and Deborah L. Guris and Savitri E. Fedson and Darrel J. Waggoner and Ivan P Moskowitz and E. M. McNally},
  journal={Circulation. Cardiovascular genetics},
  volume={2 5},
BACKGROUND Mutations in the genes encoding sarcomere proteins have been associated with both hypertrophic and dilated cardiomyopathy. Recently, mutations in myosin heavy chain (MYH7), cardiac actin (ACTC), and troponin T (TNNT2) were associated with left ventricular noncompaction, a form of cardiomyopathy characterized with hypertrabeculation that may also… CONTINUE READING