Sarcomere Formation Occurs by the Assembly of Multiple Latent Protein Complexes

@inproceedings{Rui2010SarcomereFO,
  title={Sarcomere Formation Occurs by the Assembly of Multiple Latent Protein Complexes},
  author={Yanning Rui and Jianwu Bai and Norbert Perrimon},
  booktitle={PLoS genetics},
  year={2010}
}
The stereotyped striation of myofibrils is a conserved feature of muscle organization that is critical to its function. Although most components that constitute the basic myofibrils are well-characterized biochemically and are conserved across the animal kingdom, the mechanisms leading to the precise assembly of sarcomeres, the basic units of myofibrils, are poorly understood. To gain insights into this process, we investigated the functional relationships of sarcomeric protein complexes… CONTINUE READING
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