• Corpus ID: 74714847

Sarcoma de Ewing/tumor neuroectodérmico primitivo en la cavidad nasal

@inproceedings{Garca2014SarcomaDE,
  title={Sarcoma de Ewing/tumor neuroectod{\'e}rmico primitivo en la cavidad nasal},
  author={Rafael Ord{\'o}{\~n}ez Garc{\'i}a and Mauricio Ruiz Morales},
  year={2014}
}
Ewing sarcoma / primitive neuroectodermal tumor is a rare neoplasm that belongs to the family of tumors of small round blue cells, affects men and women with a male / female ratio of 1.5:1 and have a peak incidence between 10 and 20 years. Its classic histology look with a high cellularity, composed of small, round and compact cells, giving a bluish appearance like a diffuse type lymphoma, which has served to call these also “small, round and blue cell tumors”, because stain intensely with… 
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References

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Extraskeletal Ewing’s sarcoma in a 67-year-old man

The case of a 67-year-old man with EES in the thigh whose diagnosis was confirmed histologically and cytogenetically is presented and the patient was informed that data concerning the case would be submitted for publication, and he consented.

Ewing's Sarcoma in the Nasal Cavity

The tumor discussed in this case report was immunohistochemically positive with neurogen markers (S-100 protein), and Elevated levels of p30/32 MIC2 glycoprotein can be detected in patients with Ewing’s sarcoma or peripheral neuroepthelioma.

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A new case of Ewing’s sarcoma localized to the maxillary sinus, nose and the orbit is reported, successfully treated by surgery, local high dosage radiotherapy and systemic chemotherapy.

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MIC2 is a specific marker for ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration

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Both ES and pPNET cells express the MIC2 gene in very high amounts, which represents a highly selective and almost unique feature of these cells, making an assignment of these tumors in one entity even more likely.

Immunohistochemical analysis of Ewing's sarcoma cell surface antigen p30/32MIC2.

It is indicated that HBA71 is a highly restricted cell-surface antigen of Ewing's sarcomas and primitive neuroectodermal tumors, and immunohistochemistry employing this antibody may be of value in the differential diagnosis of selected small round cell tumors in childhood and adolescence.

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