Sarcolemmal mechanisms for pHi recovery from alkalosis in the guinea-pig ventricular myocyte.

@article{Leem1998SarcolemmalMF,
  title={Sarcolemmal mechanisms for pHi recovery from alkalosis in the guinea-pig ventricular myocyte.},
  author={Chae Hun Leem and Richard D. Vaughan-Jones},
  journal={The Journal of physiology},
  year={1998},
  volume={509 ( Pt 2)},
  pages={
          487-96
        }
}
1. The mechanism of pHi recovery from an intracellular alkali load (induced by acetate prepulse or by reduction/removal of ambient PCO2) was investigated using intracellular SNARF fluorescence in the guinea-pig ventricular myocyte. 2. In Hepes buffer (pHo 7.40), pHi recovery was inhibited by removal of extracellular Cl-, but not by removal of Na+o or elevation of K+o. Recovery was unaffected by the stilbene drug DIDS (4,4-diisothiocyanatostilbene-disulphonic acid), but was slowed dose… CONTINUE READING
BETA

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…