Saralasin bolus test. Rapid screening procedure for renin-mediated hypertension.

@article{Marks1975SaralasinBT,
  title={Saralasin bolus test. Rapid screening procedure for renin-mediated hypertension.},
  author={Leonard Marks and Morton H. Maxwell and Jonathan J. Kaufman},
  journal={Lancet},
  year={1975},
  volume={2 7939},
  pages={784-7}
}
The angiotensin-blocking agent, saralasin, was given by rapid intravenous (bolus) injection to 21 hypertensive patients. A marked depressor response (average blood-pressure decrease of 30 mm Hg systolic and 20 mm Hg diastolic at 10 minutes after injection) was noted in 13 patients, of whom 11 had renovascular hypertension and 2 had high-renin essential… CONTINUE READING