Saposin Lipid Nanoparticles: A Highly Versatile and Modular Tool for Membrane Protein Research

Abstract

Saposin-derived lipid nanoparticles (SapNPs) are a new alternative tool for membrane protein reconstitution. Here we demonstrate the potential and advantages of SapNPs. We show that SapA has the lowest lipid specificity for SapNP formation. These nanoparticles are modular and offer a tunable range of size and composition depending on the stoichiometric… (More)
DOI: 10.1016/j.str.2018.01.007

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