SapF-mediated heme-iron utilization enhances persistence and coordinates biofilm architecture of Haemophilus

@inproceedings{Vogel2012SapFmediatedHU,
  title={SapF-mediated heme-iron utilization enhances persistence and coordinates biofilm architecture of Haemophilus},
  author={Andrew R. Vogel and Blake R. Szelestey and Forrest K. Raffel and Samantha W. Sharpe and Rachel L. Gearinger and Sheryl S. Justice and Kevin M. Mason},
  booktitle={Front. Cell. Inf. Microbio.},
  year={2012}
}
Non-typeable Haemophilus influenzae (NTHI) is a common commensal bacterium that resides in the human upper respiratory tract of healthy individuals. NTHI is also a known causative agent of multiple diseases including sinusitis, otitis media, as well as exacerbates disease severity of patients with cystic fibrosis and chronic obstructive pulmonary disease. We have previously shown that the Sap transporter mediates resistance to host antimicrobial peptides (AMPs) and import of the iron-containing… CONTINUE READING