Sangre de grado Croton palanostigma induces apoptosis in human gastrointestinal cancer cells.

@article{Sandoval2002SangreDG,
  title={Sangre de grado Croton palanostigma induces apoptosis in human gastrointestinal cancer cells.},
  author={Manuel Sandoval and Nataly N. Okuhama and Melinda E. Clark and Fausto M. Angeles and Juan Jos{\'e} Mart{\'i}nez Lao and Sergio Herrera Bustamante and Mark Steven Miller},
  journal={Journal of ethnopharmacology},
  year={2002},
  volume={80 2-3},
  pages={
          121-9
        }
}
Sangre de grado is an ethnomedicinal red tree sap obtained from Croton spp. that is used to treat gastrointestinal ulcers, cancer and to promote wound healing. To evaluate the potential role of sangre de grado (SdG) in cancer we examined its effects on human cancer cells, AGS (stomach), HT29 and T84 (colon). Viability of cells treated with SdG (10-200 microg/ml) decreased (P<0.01) in a dose dependent manner measured over a 24-h period. Cell proliferation at 48 h decreased (P<0.01) in all cells… CONTINUE READING
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