Sampling through time and phylodynamic inference with coalescent and birth–death models

  title={Sampling through time and phylodynamic inference with coalescent and birth–death models},
  author={Erik M. Volz and Simon D. W. Frost},
  journal={Journal of the Royal Society Interface},
  • E. Volz, S. Frost
  • Published 28 August 2014
  • Mathematics
  • Journal of the Royal Society Interface
Many population genetic models have been developed for the purpose of inferring population size and growth rates from random samples of genetic data. We examine two popular approaches to this problem, the coalescent and the birth–death-sampling model (BDM), in the context of estimating population size and birth rates in a population growing exponentially according to the birth–death branching process. For sequences sampled at a single time, we found the coalescent and the BDM gave virtually… 
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