Sampling strategies for accurate computational inferences of gametic phase across highly polymorphic major histocompatibility complex loci

Abstract

Genes of the Major Histocompatibility Complex (MHC) are very popular genetic markers among evolutionary biologists because of their potential role in pathogen confrontation and sexual selection. However, MHC genotyping still remains challenging and time-consuming in spite of substantial methodological advances. Although computational haplotype inference has… (More)
DOI: 10.1186/1756-0500-4-151

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