Sample sizes for comparative inhaled corticosteroid trials with emphasis on showing therapeutic equivalence

Abstract

In the near future it is to be expected that many new inhaled corticosteroids or formulations of these drugs will be compared with older ones, to discover whether they are therapeutically equivalent or not. The statistical evaluation of these trials differs from the classic methods. When two averages are similar or differ only slightly, power is very low… (More)
DOI: 10.1007/BF00198295

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