Sample size recalculation using conditional power.

  title={Sample size recalculation using conditional power.},
  author={Jonathan S Denne},
  journal={Statistics in medicine},
  volume={20 17-18},
The sample size required to achieve a given power at a prespecified absolute difference in mean response may depend on one or more nuisance parameters, which are usually unknown. Proposed methods for using an internal pilot to recalculate the sample size using estimates of these parameters have been well studied. Most of these methods ignore the fact that data on the parameter of interest from within this internal pilot will contribute towards the value of the final test statistic. We propose a… CONTINUE READING