Sample size calculations for cluster randomised trials. Changing Professional Practice in Europe Group (EU BIOMED II Concerted Action).

@article{Campbell2000SampleSC,
  title={Sample size calculations for cluster randomised trials. Changing Professional Practice in Europe Group (EU BIOMED II Concerted Action).},
  author={Marion K. Campbell and Jeremy M. Grimshaw and N. W. Steen},
  journal={Journal of health services research & policy},
  year={2000},
  volume={5 1},
  pages={12-6}
}
OBJECTIVES Cluster randomised trials, in which groups of individuals are randomised, are increasingly being used in the health field. Adopting a clustered approach has implications for the design of such trials, and sample size calculations need to be inflated to accommodate for the clustering effect. Reliable estimates of intracluster correlation coefficients (ICCs) are required for robust sample size calculations to be made; however, little empirical evidence is available on their likely size… CONTINUE READING

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