Sample Stability and Protein Composition of Saliva: Implications for Its Use as a Diagnostic Fluid

@inproceedings{Esser2008SampleSA,
  title={Sample Stability and Protein Composition of Saliva: Implications for Its Use as a Diagnostic Fluid},
  author={Diederik Esser and Gloria {\'A}lvarez-Llamas and Marcel P. de Vries and Desir{\'e}e Weening and Roel J Vonk and H. W. Roelofsen},
  booktitle={Biomarker insights},
  year={2008}
}
Saliva is an easy accessible plasma ultra-filtrate. Therefore, saliva can be an attractive alternative to blood for measurement of diagnostic protein markers. Our aim was to determine stability and protein composition of saliva. Protein stability at room temperature was examined by incubating fresh whole saliva with and without inhibitors of proteases and bacterial metabolism followed by Surface Enhanced Laser Desorption/Ionization (SELDI) analyses. Protein composition was determined by sodium… CONTINUE READING

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