Sample Asymmetry Analysis of Heart Rate Characteristics with Application to Neonatal Sepsis and Systemic Inflammatory Response Syndrome

@article{Kovatchev2003SampleAA,
  title={Sample Asymmetry Analysis of Heart Rate Characteristics with Application to Neonatal Sepsis and Systemic Inflammatory Response Syndrome},
  author={Boris P. Kovatchev and Leon S. Farhy and Hanqing Cao and M. Pamela Griffin and Douglas E. Lake and J. Randall Moorman},
  journal={Pediatric Research},
  year={2003},
  volume={54},
  pages={892-898}
}
We introduce the sample asymmetry analysis (SAA) and illustrate its utility for assessment of heart rate characteristics occurring early in the course of neonatal sepsis and systemic inflammatory response syndrome (SIRS). Conceptually, SAA describes changes in the shape of the histogram of RR intervals that are caused by reduced accelerations and/or transient decelerations of heart rate. Unlike other measures of heart rate variability, SAA allows separate quantification of the contribution of… 

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