Samp1 is a component of TAN lines and is required for nuclear movement.

@article{BorregoPinto2012Samp1IA,
  title={Samp1 is a component of TAN lines and is required for nuclear movement.},
  author={Joana Borrego-Pinto and Thibaud Jegou and Daniel Sampaio Os{\'o}rio and Fr{\'e}d{\'e}ric Aurad{\'e} and M{\'a}ty{\'a}s Gorj{\'a}n{\'a}cz and Birgit Koch and Iain W Mattaj and Edgar R Gomes},
  journal={Journal of cell science},
  year={2012},
  volume={125 Pt 5},
  pages={
          1099-105
        }
}
The position of the nucleus is regulated in different developmental stages and cellular events. During polarization, the nucleus moves away from the future leading edge and this movement is required for proper cell migration. Nuclear movement requires the LINC complex components nesprin-2G and SUN2, which form transmembrane actin-associated nuclear (TAN) lines at the nuclear envelope. Here we show that the nuclear envelope protein Samp1 (NET5) is involved in nuclear movement during fibroblast… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 48 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 23 REFERENCES

Similar Papers

Loading similar papers…