Salvianolic acid B-vitamin C synergy in cardiac differentiation from embryonic stem cells.

@article{Chan2009SalvianolicAB,
  title={Salvianolic acid B-vitamin C synergy in cardiac differentiation from embryonic stem cells.},
  author={Sunny Sun-Kin Chan and Jyh-Hong Chen and Shiaw-Min Hwang and I-Ju Wang and Hui-jing Li and Richard T Lee and Patrick C. H. Hsieh},
  journal={Biochemical and biophysical research communications},
  year={2009},
  volume={387 4},
  pages={723-8}
}
Inefficient cardiomyocyte differentiation limits the therapeutic use of embryonic stem (ES) cell-derived cardiomyocytes. While large collections of proprietary chemicals had been screened to improve ES cell differentiation into cardiomyocytes, the natural product library remained unexplored. Using a mouse ES cell line transfected with a cardiomyocyte-specific alpha-myosin heavy chain promoter-driven enhanced green fluorescent protein (EGFP) reporter, we screened 24 natural products with known… CONTINUE READING

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  • X. H. Ma, C. J. Zheng, L. Y. Han, B. Xie
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  • 2009
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