Salvage therapy with regimens containing ritonavir and saquinavir in extensively pretreated HIV-infected patients.

@article{Ftkenheuer1999SalvageTW,
  title={Salvage therapy with regimens containing ritonavir and saquinavir in extensively pretreated HIV-infected patients.},
  author={Gerd F{\"a}tkenheuer and Richard M. W. Hoetelmans and N Hunn and Achim Schwenk and Caspar Franzen and Markus Reiser and Alexander J{\"u}tte and Jurgen K Rockstroh and Volker Diehl and Bernd Salzberger},
  journal={AIDS},
  year={1999},
  volume={13 12},
  pages={1485-9}
}
OBJECTIVE To evaluate the efficacy and toxicity of salvage regimens containing ritonavir and saquinavir in patients failing highly active antiretroviral therapy (HAART), and to correlate outcome with plasma concentrations of protease inhibitors. DESIGN Prospective, non-randomized interventional study. SUBJECTS AND METHODS Thirty extensively pretreated HIV-infected patients with virological failure under HAART were treated with ritonavir (400 mg twice daily) and saquinavir (600 mg twice… CONTINUE READING