Salutary lessons from the Collaborative Eclampsia Trial

  title={Salutary lessons from the Collaborative Eclampsia Trial},
  author={Iain Chalmers and Adrian M. Grant},
  journal={Evidence Based Medicine},
  pages={39 - 40}
Magnesium sulphate now can be confidently recommended as the anticonvulsant of choice for eclampsia. The results of the Collaborative Eclampsia Trial (1) have shown that although its mode of action is not understood, magnesium sulfate has clear advantages when compared with both diazepam and phenytoin. Recurrent seizures were 2 to 3 times less frequent, and other seriou outcomes were also substantially reduced in comparison with phenytoin. These findings have clear implications for clinical… 
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Magnesium sulphate prevented eclampsia better than phenytoin
  • Medicine
    Evidence Based Medicine
  • 1996
A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia and its role in women's health is compared.
World Health Organization
The data and methods used to produce the Version 2 estimates of burden of hypertensive disorders of pregnancy for the year 2000 are summarized and the long-term sequelae of both preeclampsia or eClampsia are not well evaluated.
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Magnesium sulphate prevented eclampsia better thatn phenytoin [Abstract
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Magnesium sulphate prevented eclampsia better thatn phenytoin [ Abstract ]
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World Health Organization, Division of Family Health
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