Saltatory waves in the spike-diffuse-spike model of active dendritic spines.

@article{Coombes2003SaltatoryWI,
  title={Saltatory waves in the spike-diffuse-spike model of active dendritic spines.},
  author={Stephen Coombes and Paul C. Bressloff},
  journal={Physical review letters},
  year={2003},
  volume={91 2},
  pages={
          028102
        }
}
In this Letter we present the explicit construction of a saltatory traveling pulse of nonconstant profile in an idealized model of dendritic tissue. Excitable dendritic spine clusters, modeled with integrate-and-fire (IF) units, are connected to a passive dendritic cable at a discrete set of points. The saltatory nature of the wave is directly attributed to the breaking of translation symmetry in the cable. The conditions for propagation failure are presented as a function of cluster separation… CONTINUE READING

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