Salt intake determines the renal response to L-arginine infusion in normal human subjects.

@article{Barri1998SaltID,
  title={Salt intake determines the renal response to L-arginine infusion in normal human subjects.},
  author={Yousri M Barri and Christopher Stuart Wilcox},
  journal={Kidney international},
  year={1998},
  volume={53 5},
  pages={1299-304}
}
Studies in experimental animals have shown that nitric oxide (NO) generation in the kidney from L-arginine participates in adapting renal function to changes in salt intake, but similar studies in human subjects are lacking. Therefore, we compared the infusion of 30 g of L-arginine to 30 g of branched chain amino acids (control), in eight normal human subjects after 5 to 7 days of equilibration to a low salt (LS; 20 mumol.24 hr-1) or high salt (HS; 200 mumol.24 hr-1) intake. Lithium clearance… CONTINUE READING

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