Salt-induced renal injury in spontaneously hypertensive rats: effects of nebivolol.

@article{Varagi2010SaltinducedRI,
  title={Salt-induced renal injury in spontaneously hypertensive rats: effects of nebivolol.},
  author={Jasmina Varagi{\'c} and Sarfaraz Ahmad and K. Bridget Brosnihan and Javad Habibi and Roger D Tilmon and James R. Sowers and Carlos Maria Ferrario},
  journal={American journal of nephrology},
  year={2010},
  volume={32 6},
  pages={557-66}
}
BACKGROUND we investigated renal effects of nebivolol, a selective β(1)-receptor blocker with additional antioxidative ability, in spontaneously hypertensive rats (SHR) where increased salt intake induces oxidative stress and worsens renal function as a result of further activation of the renin-angiotensin and sympathetic nervous systems. METHODS male SHR were given an 8% salt diet (HS; n = 22) for 5 weeks; their age-matched controls (n = 9) received standard chow. Nebivolol was given at a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Similar Papers

Loading similar papers…