Salt-Dependent Chemotaxis of Macrophages

@inproceedings{Mller2013SaltDependentCO,
  title={Salt-Dependent Chemotaxis of Macrophages},
  author={Silke M{\"u}ller and Timothy Quast and Agnes Schr{\"o}der and Stephanie Hucke and Luisa Klotz and Jonathan Jantsch and Rupert Gerzer and Ruth Hemmersbach and Waldemar Kolanus},
  booktitle={PloS one},
  year={2013}
}
Besides their role in immune system host defense, there is growing evidence that macrophages may also be important regulators of salt homeostasis and blood pressure by a TonEBP-VEGF-C dependent buffering mechanism. As macrophages are known to accumulate in the skin of rats fed under high salt diet conditions and are pivotal for removal of high salt storage, the question arose how macrophages sense sites of high sodium storage. Interestingly, we observed that macrophage-like RAW264.7 cells… CONTINUE READING

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