Salsolinol produces reinforcing effects in the nucleus accumbens shell of alcohol-preferring (P) rats.

@article{Rodd2003SalsolinolPR,
  title={Salsolinol produces reinforcing effects in the nucleus accumbens shell of alcohol-preferring (P) rats.},
  author={Zachary A. Rodd and Richard L. Bell and Ying Zhang and Avram Goldstein and Alejandro Zaffaroni and William J H Mcbride and T K Li},
  journal={Alcoholism, clinical and experimental research},
  year={2003},
  volume={27 3},
  pages={440-9}
}
BACKGROUND The formation of salsolinol (SAL) has been hypothesized to be a factor contributing to alcoholism and alcohol abuse. If SAL is formed under chronic alcohol-drinking conditions, then it may contribute to alcohol addiction by being rewarding itself. Because SAL can be formed by the nonenzymatic condensation of acetaldehyde with dopamine, the reinforcing effects of SAL were tested in the nucleus accumbens shell, a dopamine-rich site considered to be involved in regulating alcohol… CONTINUE READING
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