Salmonid Tollip and MyD88 factors can functionally replace their mammalian orthologues in TLR-mediated trout SAA promoter activation.

@article{Rebl2011SalmonidTA,
  title={Salmonid Tollip and MyD88 factors can functionally replace their mammalian orthologues in TLR-mediated trout SAA promoter activation.},
  author={Alexander Rebl and Henrike Rebl and Shuzhen Liu and Tom Goldammer and H. -M. Seyfert},
  journal={Developmental and comparative immunology},
  year={2011},
  volume={35 1},
  pages={81-7}
}
Many functional details of the piscine Toll-like receptor (TLR) signal-mediated activation of immune defense are still elusive. We used an established reconstitution system of mammalian TLR signaling to examine if this system would allow for pathogen-dependent promoter activation of the serum amyloid A (SAA)-encoding gene from rainbow trout (Oncorhynchus… CONTINUE READING