Salmonella typhimurium apparently perceives external nitrogen limitation as internal glutamine limitation.

@article{Ikeda1996SalmonellaTA,
  title={Salmonella typhimurium apparently perceives external nitrogen limitation as internal glutamine limitation.},
  author={Toshiya Ikeda and Andrea Shauger and Sydney G Kustu},
  journal={Journal of molecular biology},
  year={1996},
  volume={259 4},
  pages={589-607}
}
Assimilation of nitrogen requires the synthesis of only two central intermediates, glutamate and glutamine, from which other compounds derive nitrogen by secondary transfers. We measured the internal pool sizes of glutamate and glutamine in Salmonella typhimurium under conditions of external nitrogen limitation or sufficiency. When growth was slowed by nitrogen limitation, the glutamine pool was lower by a factor of up to 10, whereas the glutamate pool remained high. The decrease in the… CONTINUE READING
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